Saturday, 10 December 2011

Compositions of protein receptor tyrosine kinase inhibitors

Abstract: The present invention relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same that are capable of inhibiting or antagonizing a family of receptor tyrosine kinases, Tropomysosin Related Kinases (Trk), in particular the nerve growth factor (NGF) receptor, TrkA. The invention further concerns the use of such






compounds in the treatment and/or prevention of pain, cancer, restenosis, atherosclerosis, psoriasis,

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